Phenotypic spandrel: absolute discrimination and ligand antagonism
نویسندگان
چکیده
منابع مشابه
Phenotypic spandrel: absolute discrimination and ligand antagonism.
We consider the general problem of sensitive and specific discrimination between biochemical species. An important instance is immune discrimination between self and not-self, where it is also observed experimentally that ligands just below the discrimination threshold negatively impact response, a phenomenon called antagonism. We characterize mathematically the generic properties of such discr...
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ژورنال
عنوان ژورنال: Physical Biology
سال: 2016
ISSN: 1478-3975
DOI: 10.1088/1478-3975/13/6/066011